2-(1,4-Dioxo-1,4-dihydro-2-naphthyl)-2-methylpropanoic acid

Cover Vol.14, No.2 April 2017

BA 14-2-bradley

This paper details the comparison of a built coupled volume concert hall and a computergenerated model of the hall. Coupled volume spaces typically have an auxiliary volume connected to the main volume through an acoustically transparent aperture. In this type of space, architectural parameters such as volume size and surface absorption can be designed to produce a non-linear reverberant decay,...

N-(3-Bromo-1,4-dioxo-1,4-dihydro-2-naphth­yl)-2-chloro-N-(2-chloro­benzoyl)benzamide

The title compound, C(24)H(12)BrCl(2)NO(4), was synthesized from 2-amino-3-bromo-1,4-naphthoquinone and 2-chloro-benzoyl chloride. The crystal structure shows that each of the chloro-phenyl rings is inclined at about 60° to the naphthoquinone ring system. The two chloro-phenyl rings adopt a conformation that ensures that chlorine substituents are anti so as to reduce electronic repulsion. An ex...

Lit Lunch 2/6/14

The putative eukaryotic translation initiation factor 5A (eIF5A) is a highly conserved and essential protein present in all organisms except bacteria. To be activated, eIF5A requires the conversion of a specific residue of lysine into hypusine. This hypusine modification occurs posttranslationally in two enzymatic steps, and the polyamine spermidine is the substrate. Despite having an essential...

Erratum: Vol. 14, No. 2